A 22-storey abandoned office building occupied by hundreds of squatters was engulfed in flames and collapsed in the centre of Sao Paulo early Tuesday, shooting a massive black cloud of smoke into the sky and red-hot chunks of debris into nearby structures.
At least one person died and three others were missing, a fire department spokesman said. According to authorities, 400 people were registered as living in the building, which belonged to the government.
The cause of the fire was not known, reports Reuters.
Live television images in the early morning hours showed a firefighter on an adjacent rooftop talking to a man clinging to a rescue rope and trying to escape from the upper part of the burning building.
Suddenly, the structure collapsed and the man disappeared into the rubble. Authorities said he likely died, but were searching for him. In the afternoon, firefighters continued searching for additional victims amid concrete chunks and twisted metal pipes.
An adjacent building caught fire, but was evacuated and no one was injured. That blaze was brought under control relatively quickly, Sao Paulo Fire Brigade Lieutenant André Elias told Globo TV.
The abandoned former office building had 22 storeys, according to the fire department and not 26 storeys as reported by some media. It once housed a branch of Brazil's federal police and had been occupied by squatters for the past seven years.
Sao Paulo state Governor Marcio Franca, at the scene, told the Folha de S.Paulo newspaper it was a "tragedy foretold."
The city and state governments have been working for years to forcibly remove squatters from buildings in central Sao Paulo, with plans for revitalising the area.
Franca said about 150 buildings in the region were occupied by organised groups of squatters, who have pressured the government for years to provide housing for the city's homeless.
The governor said it was legally difficult to force people to evacuate the old and decaying buildings.